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Illustration for news: Biologists at HSE University Warn of Potential Errors in MicroRNA Overexpression Method

Biologists at HSE University Warn of Potential Errors in MicroRNA Overexpression Method

Researchers at HSE University and the RAS Institute of Bioorganic Chemistry have discovered that a common method of studying genes, which relies on the overexpression of microRNAs, can produce inaccurate results. This method is widely used in the study of various pathologies, in particular cancers. Errors in experiments can lead to incorrect conclusions, affecting the diagnosis and treatment of the disease. The study findings have been published in BBA